Mapping Cancer Markers

Cancers, one of the leading causes of death worldwide, come in many different types and forms in which uncontrolled cell growth can spread to other parts of the body. Unchecked and untreated, it can ultimately lead to death. The disease is caused by genetic or environmental changes that interfere with biological mechanisms that control cell growth. These changes, as well as normal cell activities, can be detected in tissue samples through the presence of their unique chemical indicators, such as DNA and proteins, which together are known as "markers." Specific combinations of these markers may be associated with a given type of cancer.

The pattern of markers can determine whether an individual is susceptible to developing a specific form of cancer, and may also predict the progression of the disease, helping to suggest the best treatment for a given individual. For example, two patients with the same form of cancer may have different outcomes and react differently to the same treatment due to a different genetic profile. While several markers are already known to be associated with certain cancers, there are many more to be discovered, as cancer is highly heterogeneous.

Mapping Cancer Markers on World Community Grid aims to identify the markers associated with various types of cancer. The project is analyzing millions of data points collected from thousands of healthy and cancerous patient tissue samples. These include tissues with lung, ovarian, prostate, pancreatic and breast cancers. By comparing these different data points, researchers aim to identify patterns of markers for different cancers and correlate them with different outcomes, including responsiveness to various treatment options.




This knowledge can help researchers and physicians to:

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Improve and personalize cancer treatment: by making it possible to detect cancer earlier, identify high-risk patients, and to customize treatment based on a patient's personal genetic profile.

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Accelerate cancer research and improve the overall process for identifying markers: by refining the process of identifying markers, researchers can determine an individual patient's markers more easily, and future large sets of data can be analyzed more efficiently.

http://www.worldcommunitygrid.or ... w.do?language=zh_CN
後來 我總算學會了 如何去愛 可惜你 早已遠去 消失在人海   後來 終於在眼淚中明白 有些人 一旦錯過就不再


PC-Infinity World Community Grid Team
Re: MCM Progress Reports
Hello World Community Grid members,

As currently planned, over the course of the project, MCM will proceed in four phases, analyzing a different cancer dataset in each phase. The first (and current) phase is focused on lung cancer. So far, MCM work units have explored the space of lung cancer signatures that are composed of 10-20 genetic markers at a time.

We estimate about 350,000,000 work units in total for the project (counting redundancy) -- about 80,000,000 to 100,000,000 work units per cancer.

We are delighted by the incredible response to this project. Thank you all for making this project possible with your enthusiasm and your donated CPU cycles.

Christian A. Cumbaa
Research Associate
Ontario Cancer Institute / University Health Network
後來 我總算學會了 如何去愛 可惜你 早已遠去 消失在人海   後來 終於在眼淚中明白 有些人 一旦錯過就不再


PC-Infinity World Community Grid Team
Project roadmap and first phase results from the Mapping Cancer Markers team
https://secure.worldcommunitygri ... le.do?articleId=369
後來 我總算學會了 如何去愛 可惜你 早已遠去 消失在人海   後來 終於在眼淚中明白 有些人 一旦錯過就不再


PC-Infinity World Community Grid Team
後來 我總算學會了 如何去愛 可惜你 早已遠去 消失在人海   後來 終於在眼淚中明白 有些人 一旦錯過就不再


PC-Infinity World Community Grid Team
11037
csc 發表於 2014-9-29 20:26
係唔係D結果未驗證,所以平均分下降
後來 我總算學會了 如何去愛 可惜你 早已遠去 消失在人海   後來 終於在眼淚中明白 有些人 一旦錯過就不再


PC-Infinity World Community Grid Team
新項目- Uncovering Genome Mysteries
http://www.worldcommunitygrid.org/research/ugm1/overview.do

這些結果將有助於科學家以下任務:
•發現新蛋白的功能和充實對一般的生化過程的知識
•生物識別與對方和環境如何相互作用
•記錄當前基線微生物多樣性,允許更好地了解微生物在環境壓力,如氣候變化如何改變
•理解和模擬複雜的微生物系統
此外,更好地理解這些生物和它們的蛋白質和酶將可能是在開發新的藥物,利用新的可再生能源,改善營養,清潔的環境,創造綠色工業過程和許多其他有用的進展。
上述中文由google 翻譯
後來 我總算學會了 如何去愛 可惜你 早已遠去 消失在人海   後來 終於在眼淚中明白 有些人 一旦錯過就不再


PC-Infinity World Community Grid Team